文献笔记-香草杏仁

A disease-driver population within interstitial cells of human calcific aortic valves identified via single-cell and proteomic profiling （Cell Reports IF=9.4）

'single-cell RNA seq'，'干细胞与转分化'。参与CAVD疾病驱动VICs亚群DDP-VICs（CD44^high^CD29^+^CD59^+^CD73^+^CD45^low^）总结作者通过高通量流式检测鉴定出一个参与CAVD疾病驱动VICs...

# 钙化 # 细胞 # 表达

Vamond2年前

051180

Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field

Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field Article type: Review Files: CIRCRESAHA.116.310060.pdf Publication Year: 201...

# 钙化 # 细胞 # 磷酸盐

Vamond2年前

050720

Maturation of heart valve cell populations during postnatal remodeling

Maturation of heart valve cell populations during postnatal remodeling Article type: Original Article Institute: The Heart Institute, Division of Molecular Cardiovascular Biology, ...

# 细胞 # 瓣膜 # 心脏

Vamond2年前

049290

Resistin: Potential biomarker and therapeutic target in atherosclerosis

Zhou, Li, Jun-Yi Li, Ping-Ping He, Xiao-Hua Yu, and Chao-Ke Tang. “Resistin: Potential Biomarker and Therapeutic Target in Atherosclerosis.” Clinica Chimica Acta; International J...

# 细胞 # 表达 # 抵抗素

Vamond2年前

048850

EHJ：活化的血小板促进成骨并推动钙化性主动脉瓣狭窄的进展

本研究探讨了活化血小板对钙化性主动脉瓣狭窄（CAVS）进展的影响。结果显示，活化血小板通过分泌ADP促进心脏瓣膜间质细胞（VICs）的成骨程序，进一步导致钙化。研究利用多种技术（如SEM、免疫荧...

# 钙化 # 主动脉瓣 # 血小板

Vamond3年前

047770

Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity

主要研究结果 SORT1与AS的遗传关联对SORT1基因组50kb范围的555个变体进行meta分析： 11个变体与AS显著相关，但可能仅包含一个独立的信号 sortlin缺失减弱主动脉瓣狭窄的发展并...

# 钙化 # 细胞 # 表达

Vamond2年前

047770

Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk.

Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk. Zhou Q, Cao H, Hang X, Liang H, Zhu M, Fan Y, Shi J, Dong N, He X. Midkine Prevents C...

# 钙化 # 细胞 # 分析

Vamond2年前

047410