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A disease-driver population within interstitial cells of human calcific aortic valves identified via single-cell and proteomic profiling (Cell Reports IF=9.4)
'single-cell RNA seq','干细胞与转分化'。参与CAVD疾病驱动VICs亚群DDP-VICs(CD44^high^CD29^+^CD59^+^CD73^+^CD45^low^) 总结 作者通过高通量流式检测鉴定出一个参与CAVD疾病驱动VICs...
Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field
Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field Article type: Review Files: CIRCRESAHA.116.310060.pdf Publication Year: 201...
Maturation of heart valve cell populations during postnatal remodeling
Maturation of heart valve cell populations during postnatal remodeling Article type: Original Article Institute: The Heart Institute, Division of Molecular Cardiovascular Biology, ...
Resistin: Potential biomarker and therapeutic target in atherosclerosis
Zhou, Li, Jun-Yi Li, Ping-Ping He, Xiao-Hua Yu, and Chao-Ke Tang. “Resistin: Potential Biomarker and Therapeutic Target in Atherosclerosis.” Clinica Chimica Acta; International J...
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity
主要研究结果 SORT1与AS的遗传关联 对SORT1基因组50kb范围的555个变体进行meta分析: 11个变体与AS显著相关,但可能仅包含一个独立的信号 sortlin缺失减弱主动脉瓣狭窄的发展并...
Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk.
Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk. Zhou Q, Cao H, Hang X, Liang H, Zhu M, Fan Y, Shi J, Dong N, He X. Midkine Prevents C...