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Resistin: Potential biomarker and therapeutic target in atherosclerosis
Zhou, Li, Jun-Yi Li, Ping-Ping He, Xiao-Hua Yu, and Chao-Ke Tang. “Resistin: Potential Biomarker and Therapeutic Target in Atherosclerosis.” Clinica Chimica Acta; International J...
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity
主要研究结果 SORT1与AS的遗传关联 对SORT1基因组50kb范围的555个变体进行meta分析: 11个变体与AS显著相关,但可能仅包含一个独立的信号 sortlin缺失减弱主动脉瓣狭窄的发展并...
Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk.
Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk. Zhou Q, Cao H, Hang X, Liang H, Zhu M, Fan Y, Shi J, Dong N, He X. Midkine Prevents C...
EHJ:活化的血小板促进成骨并推动钙化性主动脉瓣狭窄的进展
本研究探讨了活化血小板对钙化性主动脉瓣狭窄(CAVS)进展的影响。结果显示,活化血小板通过分泌ADP促进心脏瓣膜间质细胞(VICs)的成骨程序,进一步导致钙化。研究利用多种技术(如SEM、免疫荧...