EHJ：活化的血小板促进成骨并推动钙化性主动脉瓣狭窄的进展
本研究探讨了活化血小板对钙化性主动脉瓣狭窄（CAVS）进展的影响。结果显示，活化血小板通过分泌ADP促进心脏瓣膜间质细胞（VICs）的成骨程序，进一步导致钙化。研究利用多种技术（如SEM、免疫荧...
Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk.
Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk. Zhou Q, Cao H, Hang X, Liang H, Zhu M, Fan Y, Shi J, Dong N, He X. Midkine Prevents C...
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity
主要研究结果 SORT1与AS的遗传关联 对SORT1基因组50kb范围的555个变体进行meta分析： 11个变体与AS显著相关，但可能仅包含一个独立的信号 sortlin缺失减弱主动脉瓣狭窄的发展并...
Resistin: Potential biomarker and therapeutic target in atherosclerosis
Zhou, Li, Jun-Yi Li, Ping-Ping He, Xiao-Hua Yu, and Chao-Ke Tang. “Resistin: Potential Biomarker and Therapeutic Target in Atherosclerosis.” Clinica Chimica Acta; International J...
Maturation of heart valve cell populations during postnatal remodeling
Maturation of heart valve cell populations during postnatal remodeling Article type: Original Article Institute: The Heart Institute, Division of Molecular Cardiovascular Biology, ...
Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field
Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field Article type: Review Files: CIRCRESAHA.116.310060.pdf Publication Year: 201...
A disease-driver population within interstitial cells of human calcific aortic valves identified via single-cell and proteomic profiling （Cell Reports IF=9.4）
'single-cell RNA seq'，'干细胞与转分化'。参与CAVD疾病驱动VICs亚群DDP-VICs（CD44^high^CD29^+^CD59^+^CD73^+^CD45^low^） 总结 作者通过高通量流式检测鉴定出一个参与CAVD疾病驱动VICs...
Ubuntu防火墙配置
Created time: December 22, 2021 7:49 PM 参考链接: https://blog.csdn.net/willingtolove/article/details/109863064 Ubuntu系统默认是安装了ufw防火墙的。查看防火墙的状态： sudo ufw ...
linux常用命令: systemctl
linux系统结构/lib/systemd/system目录 根据 Linux 惯例，字母d是守护进程（daemon）的缩写。 Systemd 这个名字的含义，就是它要守护整个系统。 该目录自动存放启动文件的配置位置，里...
linux添加环境变量
"Linux笔记" ubuntu 在用户主目录下有一个 .bashrc 隐藏文件，可以在此文件中加入 PATH 的设置如下： sudo vim ~/.bashrc 加入： export PATH=<你的要加入的路径>:$PATH e...